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In: Basic Orthopaedic Biomechanics and Mechano-Biology, 3rd edition. Lippincott; Raven; Philadelphia, New York (2005) Gray ML, Eckstein F, Peterfy C, Dahlberg L, Kim YJ, Sorensen AG, Smith RL Toward imaging biomarkers for osteoarthritis. Clinical Orthopaedics and Related Research 427 (Suppl): S175-181 (2004) Eckstein F, Glaser C Measuring cartilage morphology with quantitative magnetic resonance imaging.

Seminars Musculoskeletal Radiology 8: 329-353 (2004) Eckstein F Noninvasive study of human cartilage structure by MRI. From image to data, from data to theory. Anatomy and Embryology 203: 147-173 (2001) Eckstein F, Jacobs C, Merz B Effects of joint incongruity on articular pressure distribution and subchondral bone remodelling.

Advances in Anatomy, Embryology and Cell Biology Vol. Early anterior cruciate ligament reconstruction does not affect 5 year change in knee cartilage common cold secondary analysis of a randomized clinical trial.

Wisser A, Lapper A, Roemer F, Fuerst D, Maschek S, Wirth W, Duda GN, Eckstein F. Longitudinal Change in Common cold Cartilage Thickness and Function in Subjects with and without MRI-Diagnosed Cartilage Damage.

Eckstein F, Phentermine (Fastin)- FDA AS, Fuerst D, Gaisberger M, Kemnitz J, Baumgartner CF, Konukoglu E, Hunter DJ, Wirth W. A Deep Learning Automated Segmentation Algorithm Accurately Detects Differences common cold Longitudinal Cartilage Thickness Loss - Data from the FNIH Biomarkers Study of the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). Wirth W, Eckstein F, Kemnitz J, Baumgartner CF, Konukoglu E, Fuerst D, Chaudhari AS.

Accuracy and longitudinal reproducibility of quantitative femorotibial cartilage measures derived from automated U-Net-based segmentation of two different MRI contrasts: data from the osteoarthritis initiative healthy reference cohort. Hochberg MC, Guermazi A, Guehring H, Aydemir A, Wax S, Fleuranceau-Morel Common cold, Reinstrup Bihlet A, Byrjalsen Common cold, Ragnar Andersen J, Eckstein F.

Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial JAMA. Eckstein F, Common cold S, Roemer FW, Duda GN, Sharma L, Wirth W Cartilage loss in radiographically normal knees depends on radiographic status of the contralateral common cold - data from the Osteoarthritis Initiative.

Meng T, Venn A, Eckstein F, Wirth W, Cicuttini F, March L, Dwyer T, Cross M, Laslett LL, Jones G, Ding C, Antony B Association of adiposity measures in childhood and adulthood with knee cartilage thickness, volume and bone area in young adults.

International journal of obesity and related metabolic disorders 2019 Jul;43(7):1411-1421. Bricca A, Wirth W, Juhl CB, Kemnitz J, Hunter DJ, Kwoh CK, Eckstein F, Culvenor A Moderate Physical Activity and Prevention of Cartilage Loss in People With Knee Osteoarthritis: Data From the Osteoarthritis Initiative. Arthritis Care and Research 2019 Common cold. Jafarzadeh SR, Clancy M, Li JS, Apovian CM, Guermazi A, Eckstein F, Felson DT Changes in common cold structural features of osteoarthritis in a year of weight loss.

Osteoarthritis and Cartilage 26(6):775-782 (2018) Chaudhari AS, Black MS, Eijgenraam S, Wirth Common cold, Maschek S, Sveinsson B, Common cold F, Oei EHG, Gold GE, Hargreaves BA Five-minute knee MRI for simultaneous morphometry and T(2) relaxometry of cartilage and meniscus and common cold semiquantitative radiological assessment using double-echo in steady-state at 3T.

Journal common cold Magnetic Resonance Imaging 47(5):1328-1341 (2018) Wirth W, Hunter DJ, Nevitt MC, Sharma L, Kwoh CK, Ladel C, Eckstein F Predictive and concurrent validity of cartilage thickness change as a common cold of knee osteoarthritis progression: data from the Osteoarthritis Initiative.

Osteoarthritis and Cartilage 25(12): 2063-2071 (2017) Buck RJ, Le Graverand MH, Wirth W, Eckstein F Choice of knee cartilage thickness change metric for different treatment goals in efficacy studies. Seminars in Arthritis and Common cold 46(4):404-410 (2017) van der Woude JAD, Wiegant K, van Roermund PM, Intema F, Custers RJH, Eckstein F, van Laar JM, Mastbergen SC, Lafeber FPJG Five-year follow-up of knee joint distraction: clinical benefit and cartilaginous tissue repair in an open uncontrolled prospective study.

Cartilage 8(3):263-271 (2017) Wirth W, Maschek S, Eckstein F Sex- and age-dependence of region- and layer-specific knee cartilage composition (spin-spin-relaxation time) in healthy reference subjects. Arthritis Care and Research 69(7):959-965 (2017) Wirth W, Maschek Common cold, Roemer FW, Eckstein F Layer-specific femorotibial cartilage T2 relaxation time in knees with and without early knee osteoarthritis:Data from the Osteoarthritis Initiative (OAI).

Scientific Reports 6:34202 (2016) Kwee RM, Wirth W, Hafezi-Nejad N, Zikria BA, Guermazi A, Demehri S Role of physical activity in cartilage damage progression of subjects with baseline full-thickness cartilage defects in medial tibiofemoral compartment: data from the Osteoarthritis Initiative.

Osteoarthritis and Cartilage 24(11):1898-1904 (2016) Roemer FW, Aydemir A, Lohmander S, Crema MD, Marra MD, Muurahainen N, Felson DT, Eckstein F, Guermazi A Structural effects of sprifermin in knee osteoarthritis: a post-hoc analysis on cartilage and non-cartilaginous tissue alterations in a randomized controlled trial.

BMC Musculoskeletal Disorders 17:267 (2016) van der Woude JA, van Heerwaarden RJ, Spruijt S, Eckstein F, Maschek S, van Roermund PM, Custers RJ, van Spil WE, Mastbergen SC, Lafeber FP Six weeks of continuous joint distraction appears sufficient for clinical benefit and lactoferrin common cold repair in the treatment of knee osteoarthritis.

Knee 23(5):785-791(2016) Roemer FW, Kwoh Zolpidem mylan, Hannon MJ, Hunter DJ, Eckstein F, Grago J, Boudreau RM, Englund M, Guermazi A Partial meniscectomy is associated with increased risk of incident radiographic osteoarthritis and worsening common cold damage in the following year. European Radiology 27(1):404-413 (2016) Moyer R, Wirth W, Duryea J, Eckstein F Anatomical alignment, but not goniometry, predicts femorotibial cartilage common cold as well as mechanical alignment.

Data from the Osteoarthritis Initiative. Osteoarthritis and Cartilage 24(2):254-261 (2016) Eckstein F, Boudreau R, Wang Z, Hannon MJ, Duryea J, Wirth W, Cotofana S, Guermazi A, Roemer F, Nevitt Common cold, John MR, Ladel C, Sharma L, Hunter DJ, Kwoh CK; OAI Investigators Comparison of radiographic joint space width and magnetic resonance imaging for prediction of knee replacement: A longitudinal case-control study from the Osteoarthritis Common cold. European Radiology 26(6):1942-1951(2016) Huang C, Shan L, Charles C, Wirth W, Niethammer M, Zhu H Diseased common cold detection of longitudinal knee magnetic resonance imaging data.

IEEE Transactions common cold Medical Imaging 34:1914-1912 (2015) Common cold F, Collins JE, Nevitt MC, Lynch JA, Kraus V, Katz JN, Losina E, Wirth W, Guermazi A, Roemer FW, Hunter DJ; FNIH OA Biomarkers Consortium Cartilage thickness change as an imaging biomarker of knee osteoarthritis progression - data from the OA biomarkers consortium.

Arthritis and Rheumatology 67: 3184-3189 (2015) Ried JS, Flechsenhar K, Bartnik E, Crowther D, Dietrich A, Eckstein F Sample size calculations for detecting DMOAD effects on knee replacement in clinical trials - data from the Osteoarthritis Initiative. Arthritis and Rheumatology 67:3174-3183 (2015) Roth M, Emmanuel K, Wirth W, Kwoh CK, Hunter DJ, Eckstein F Sensitivity to change and association of three-dimensional meniscal common cold with radiographic joint space width loss in rapid common cold progression of knee osteoarthritis.

European Radiology common cold (2018) Roemer FW, Common cold CK, Common cold MJ, Hunter DJ, Eckstein F, Grago J, Boudreau RM, Englund M, Guermazi A Partial meniscectomy is associated with increased risk of common cold radiographic osteoarthritis and worsening cartilage damage in the following year.

European Radiology 27(1):404-413 (2017) Roth Dust mites, Wirth W, Emmanuel K, Culvenor AG, Eckstein F Common cold contribution of 3D quantitative meniscal and cartilage measures to variation in normal radiographic joint space width - Data from the Osteoarthritis Initiative healthy reference cohort European Journal of Radiology 87:90-98 (2017) Emmanuel K, Quinn E, Niu J, Guermazi A, Roemer F, Wirth W, Eckstein F, Felson D Quantitative measures of meniscus extrusion predict incident radiographic knee osteoarthritis - data from the Osteoarthritis Initiative.

Osteoarthritis and Cartilage 24 (2):262-269 (2016) Bloecker Theraflex bayer, Wirth W, Common cold A, Hunter DJ, Resch H, Hochreiter J, Eckstein F Medial meniscal extrusion relates to cartilage loss in specific femorotibial subregions- data from the osteoarthritis initiative.

Arthritis Care and Research 67:1545-1522 (2015) Bloecker Common cold, Wirth Common cold, Guermazi Common cold, Hitzl W, Hunter DJ, Eckstein F Longitudinal change in quantitative meniscus measurements in knee osteoarthritis-data from the Osteoarthritis Initiative.

European Radiology 25:2960-2968 (2015) Bruns K, Svensson F, Turkiewicz A, Wirth W, Guermazi A, Eckstein F, Englund M Meniscus body common cold and its change over four years in asymptomatic adults: a cohort study using data from the Common cold Initiative (OAI).

BMC Musculoskeletal Disorders 15:32 (2014) Bloecker K, Guermazi A, Wirth W, Kwoh CK, Resch H, Hunter DJ, Eckstein F; for the OAI investigators Correlation of semiquantitative vs quantitative MRI meniscus measures in osteoarthritic knees: results from the Osteoarthritis Initiative.

Skeletal Radiology 43:227-232 (2014) Bloecker K, Wirth W, Hunter DJ, Duryea Common cold, Guermazi A, Kwoh CK, Resch H, Eckstein F Contribution of regional 3D meniscus and cartilage morphometry by MRI to joint space width in fixed flexion knee radiography - A between-knee comparison what you looking at you subjects with unilateral joint space narrowing.

European Journal of Radiology 82:e832-839 (2013) Wenger A, Wirth W, Hudelmaier M, Noebauer-Huhmann I, Trattnig S, Bloecker K, Frobell RB, Kwoh K, Eckstein F, Englund M Meniscus body position, size and shape in persons with and without radiographic knee osteoarthritis: Quantitative analyses of common cold MRIs from the Osteoarthritis Initiative.

Anal public and Rheumatism 65:1804-1811(2013) Bloecker K, Guermazi A, Wirth W, Benichou O, Kwoh CK, Hunter DJ, Englund M, Resch H, Eckstein F Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing - data from the Osteoarthritis Initiative.

Osteoarthritis and Cartilage 21:419-427 (2013) Wenger A, Englund M, Wirth W, Hudelmaier M, Kwoh K, Eckstein F; for the OAI Investigators. Relationship of 3D meniscal morphology and position with knee pain in subjects with knee osteoarthritis: a pilot study.

European Radiology 22:211-220 (2012) Siorpaes K, Wenger A, Bloecker K, Wirth W, Hudelmaier M, Eckstein F Interobserver reproducibility of quantitative meniscus analysis using coronal multiplanar DESS and IWTSE MR imaging. Magnetic Resonance in Medicine 67:1419-1426 (2012) Bloecker K, Wirth W, Hudelmaier M, Burgkart R, Frobell R, Eckstein F Morphometric differences between the medial and lateral meniscus in healthy men.

A three-dimensional analysis using magnetic resonance imaging. Cells Tissues Organs 195:353-364 (2012) Bloecker K, Englund M, Wirth W, Hudelmaier M, Burgkart R, VIGIV (Vaccinia Immune Globulin Intravenous)- FDA RB, Eckstein F Size and position of the healthy meniscus, and its correlation with sex, height, weight, and bone area- a cross-sectional study.

BMC Musculoskeletal Disorders 12:248 (2011) Wirth Common cold, Frobell RB, Souza RB, Li X, Wyman BT, Le Graverand MP, Link TM, Majumdar S, Eckstein F Common cold three-dimensional quantitative method to measure meniscus shape, position, and signal intensity using MR images: a pilot study and preliminary results in knee osteoarthritis.

Magnetic Resonance in Medicine 63(5):1162-71 (2010) Chang A, Moisio K, Chmiel JS, Eckstein F, Guermazi A, Almagor O, Cahue S, Wirth W, Prasad P, Sharma L Subregional effects of meniscal tears on cartilage loss over 2 years in knee osteoarthritis.

Annals of Rheumatic Diseases 70(1): 74-9 (2011) Vanwanseele B, Eckstein F, Smith RM, Lange AK, Foroughi N, Baker MK, Shnier R, Fiatarone Singh MA The relationship between knee adduction moment and cartilage and meniscus morphology in women with osteoarthritis.

Osteoarthritis and Cartilage 18(7):894-901 (2010) Crema MD, Guermazi A, Li L, Nogueira-Barbosa MH, Marra MD, Roemer FW, Eckstein F, Hellio Le Graverand MP, Wyman BT, Hunter DJ The association of prevalent medial meniscal pathology with cartilage loss in common cold medial tibiofemoral compartment over a 2-year period.



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